<

American Serenade September 2026 Itinerary

For more information, prices, and detailed day-by-day American Serenade itineraries in September 2026, please click one of the scheduled American Serenade sailing dates below.

Get FREE Price Alerts

Subscribe to our weekly cruise deals email and enjoy FREE price change alerts and updates for this cruise and others like it.

We promise to protect your privacy and personal data. You can review our privacy policy here.

Sail Date

Itinerary Name and Ports

Duration

Save to Favorites

Priced From(per person)

Sep 4, 2026

(Friday)

8 Night Upper Mississippi River Cruise

From Alton to St Paul, Minnesota

Ports: Alton, Cruising the Mississippi River, Hannibal, Cruising the Mississippi River, Muscatine, Dubuque, Winona, Red Wing, St Paul

8 Nights

Add to Favorites
Compare Favorites
$5,635

Balcony (double occupancy)

Includes taxes & feesLearn More
Sep 18, 2026

(Friday)

8 Night Upper Mississippi River Cruise

From Alton to St Paul, Minnesota

Ports: Alton, Cruising the Mississippi River, Hannibal, Cruising the Mississippi River, Muscatine, Dubuque, Winona, Red Wing, St Paul

8 Nights

Add to Favorites
Compare Favorites
$5,635

Balcony (double occupancy)

Includes taxes & feesLearn More
Sep 25, 2026

(Friday)



15 Night Grand Heartland Cruise and Land Tour

From St Paul, Minnesota to New Orleans, Louisiana

Ports: St Paul, Cruising the Mississippi River, La Crosse, Dubuque, Davenport Iowa, River Cruising, Hannibal, River Cruising, St Louis, Memphis, Tunica, Cruising the Mississippi River, Vicksburg, Natchez, Baton Rouge, New Orleans

15 Nights

Add to Favorites
Compare Favorites
$11,945

Balcony (double occupancy)

Includes taxes & feesLearn More

Browse American Serenade Itineraries by Month

Overlay Title