Get FREE Price Alerts

Subscribe to our weekly cruise deals email and enjoy FREE price change alerts and updates for this cruise and others like it.

We promise to protect your privacy and personal data. You can review our privacy policy here.

Modify Your Choices
Vacation Type


Filters
Destination
- Any Destination
Travel Dates
Narrow Date Range
Departure Port
- All Departure Ports
Cruise Length
- All Durations
Cruise Line
- American Cruise Lines
Cruise Ships
- All Cruise Ships

Search Results


Sailings per page
846 Matched Sailings
Departing
Itinerary and Ship
Length
Save to
Favorites
Priced from

Apr 30, 2025

(Wednesday)

5 Night Highlights of the Columbia River Cruise

American West
American Cruise Lines
Starts: Portland, Oregon
Ends: Portland, Oregon
Ports of Call:
Portland, Cruising the Columbia River Gorge, Astoria, Kalama Washington, Stevenson, Portland

5 Nights


Add to Favorites
Compare Favorites
from

$2,940

per person
(double occupancy)
Includes taxes & fees
Learn More

Dec 13, 2024

(Friday)

7 Night Historic Mississippi River Cruise and Land Tour

American Symphony
American Cruise Lines
Starts: New Orleans, Louisiana
Ends: New Orleans, Louisiana
Ports of Call:
New Orleans, Cruising the Mississippi River, Oak Alley, Houmas House, Baton Rouge, Natchez...

7 Nights


Add to Favorites
Compare Favorites
from

$4,255

per person
(double occupancy)
Includes taxes & fees
Learn More

Nov 16, 2025

(Sunday)

7 Night Historic Mississippi River Cruise and Land Tour

American Serenade
American Cruise Lines
Starts: New Orleans, Louisiana
Ends: New Orleans, Louisiana
Ports of Call:
New Orleans, Cruising the Mississippi River, Oak Alley, Houmas House, Baton Rouge, Natchez...

7 Nights


Add to Favorites
Compare Favorites
from

$4,255

per person
(double occupancy)
Includes taxes & fees
Learn More

Nov 28, 2025

(Friday)

7 Night Historic Mississippi River Cruise and Land Tour

American Melody
American Cruise Lines
Starts: New Orleans, Louisiana
Ends: New Orleans, Louisiana
Ports of Call:
New Orleans, Cruising the Mississippi River, Oak Alley, Houmas House, Baton Rouge, Natchez...

7 Nights


Add to Favorites
Compare Favorites
from

$4,255

per person
(double occupancy)
Includes taxes & fees
Learn More

Dec 04, 2025

(Thursday)

7 Night Historic Mississippi River Cruise and Land Tour

American Melody
American Cruise Lines
Starts: New Orleans, Louisiana
Ends: New Orleans, Louisiana
Ports of Call:
New Orleans, Cruising the Mississippi River, Oak Alley, Houmas House, Baton Rouge, Natchez...

7 Nights


Add to Favorites
Compare Favorites
from

$4,255

per person
(double occupancy)
Includes taxes & fees
Learn More

Dec 10, 2025

(Wednesday)

7 Night Historic Mississippi River Cruise and Land Tour

American Melody
American Cruise Lines
Starts: New Orleans, Louisiana
Ends: New Orleans, Louisiana
Ports of Call:
New Orleans, Cruising the Mississippi River, Oak Alley, Houmas House, Baton Rouge, Natchez...

7 Nights


Add to Favorites
Compare Favorites
from

$4,255

per person
(double occupancy)
Includes taxes & fees
Learn More

Dec 16, 2025

(Tuesday)

7 Night Historic Mississippi River Cruise and Land Tour

American Melody
American Cruise Lines
Starts: New Orleans, Louisiana
Ends: New Orleans, Louisiana
Ports of Call:
New Orleans, Cruising the Mississippi River, Oak Alley, Houmas House, Baton Rouge, Natchez...

7 Nights


Add to Favorites
Compare Favorites
from

$4,255

per person
(double occupancy)
Includes taxes & fees
Learn More

Mar 10, 2025

(Monday)

7 Night Historic Mississippi River Cruise and Land Tour

American Melody
American Cruise Lines
Starts: New Orleans, Louisiana
Ends: New Orleans, Louisiana
Ports of Call:
New Orleans, Cruising the Mississippi River, Oak Alley, Houmas House, Baton Rouge, Natchez...

7 Nights


Add to Favorites
Compare Favorites
from

$4,565

per person
(double occupancy)
Includes taxes & fees
Learn More

Mar 16, 2025

(Sunday)

7 Night Historic Mississippi River Cruise and Land Tour

American Melody
American Cruise Lines
Starts: New Orleans, Louisiana
Ends: New Orleans, Louisiana
Ports of Call:
New Orleans, Cruising the Mississippi River, Oak Alley, Houmas House, Baton Rouge, Natchez...
Theme Cruise

7 Nights


Add to Favorites
Compare Favorites
from

$4,565

per person
(double occupancy)
Includes taxes & fees
Learn More

Mar 22, 2025

(Saturday)

7 Night Historic Mississippi River Cruise and Land Tour

American Melody
American Cruise Lines
Starts: New Orleans, Louisiana
Ends: New Orleans, Louisiana
Ports of Call:
New Orleans, Cruising the Mississippi River, Oak Alley, Houmas House, Baton Rouge, Natchez...

7 Nights


Add to Favorites
Compare Favorites
from

$4,565

per person
(double occupancy)
Includes taxes & fees
Learn More

Mar 28, 2025

(Friday)

8 Night Southeast Sea Islands Cruise and Land Tour

American Independence
American Cruise Lines
Starts: Charleston, South Carolina
Ends: Jacksonville, Florida
Ports of Call:
Charleston, Beaufort, Hilton Head Island SC, Savannah, Cruising the Atlantic Intracoastal Waterway...

8 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

Mar 21, 2025

(Friday)

8 Night Southeast Sea Islands Cruise and Land Tour

American Independence
American Cruise Lines
Starts: Fernandina Beach, Florida
Ends: Charleston, South Carolina
Ports of Call:
Fernandina Beach, Jekyll Island GA, Cruising the Atlantic Intracoastal Waterway, Savannah...

8 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

May 03, 2025

(Saturday)

7 Night Chesapeake Bay Cruise

American Independence
American Cruise Lines
Starts: Baltimore, Maryland
Ends: Baltimore, Maryland
Ports of Call:
Baltimore, Yorktown, Williamsburg, Yorktown, Chesapeake Bay, Cambridge, St Michaels...

7 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

May 10, 2025

(Saturday)

7 Night Chesapeake Bay Cruise

American Independence
American Cruise Lines
Starts: Baltimore, Maryland
Ends: Baltimore, Maryland
Ports of Call:
Baltimore, Yorktown, Williamsburg, Yorktown, Chesapeake Bay, Cambridge, St Michaels...

7 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

May 17, 2025

(Saturday)

7 Night Chesapeake Bay Cruise

American Independence
American Cruise Lines
Starts: Baltimore, Maryland
Ends: Baltimore, Maryland
Ports of Call:
Baltimore, Yorktown, Williamsburg, Yorktown, Chesapeake Bay, Cambridge, St Michaels...

7 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

Jul 25, 2025

(Friday)

8 Night Ohio River Cruise

American Heritage
American Cruise Lines
Starts: Pittsburgh, Pennsylvania
Ends: Louisville, Kentucky
Ports of Call:
Pittsburgh, Moundsville, Marietta, Cruising the Ohio River, Maysville, Cincinnati, Louisville

8 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

Aug 08, 2025

(Friday)

8 Night Ohio River Cruise

American Heritage
American Cruise Lines
Starts: Pittsburgh, Pennsylvania
Ends: Louisville, Kentucky
Ports of Call:
Pittsburgh, Moundsville, Marietta, Cruising the Ohio River, Maysville, Cincinnati, Louisville

8 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

May 02, 2026

(Saturday)

7 Night Potomac River and Chesapeake Bay Cruise

American Independence
American Cruise Lines
Starts: Baltimore, Maryland
Ends: Washington DC, District of Columbia
Ports of Call:
Baltimore, Annapolis Maryland, St Michaels, Cambridge, Chesapeake Bay, Yorktown, Mount Vernon...

7 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

May 09, 2026

(Saturday)

7 Night Potomac River and Chesapeake Bay Cruise

American Independence
American Cruise Lines
Starts: Washington DC, District of Columbia
Ends: Baltimore, Maryland
Ports of Call:
Washington DC, Yorktown, Chesapeake Bay, Cambridge, St Michaels, Annapolis Maryland, Baltimore

7 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

May 16, 2026

(Saturday)

7 Night Potomac River and Chesapeake Bay Cruise

American Independence
American Cruise Lines
Starts: Baltimore, Maryland
Ends: Washington DC, District of Columbia
Ports of Call:
Baltimore, Annapolis Maryland, St Michaels, Cambridge, Chesapeake Bay, Yorktown, Mount Vernon...

7 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

May 23, 2026

(Saturday)

7 Night Potomac River and Chesapeake Bay Cruise

American Independence
American Cruise Lines
Starts: Washington DC, District of Columbia
Ends: Baltimore, Maryland
Ports of Call:
Washington DC, Yorktown, Chesapeake Bay, Cambridge, St Michaels, Annapolis Maryland, Baltimore

7 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

May 30, 2026

(Saturday)

7 Night Chesapeake Bay Cruise

American Independence
American Cruise Lines
Starts: Baltimore, Maryland
Ends: Baltimore, Maryland
Ports of Call:
Baltimore, Yorktown, Williamsburg, Yorktown, Chesapeake Bay, Cambridge, St Michaels...

7 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

Jun 06, 2026

(Saturday)

7 Night Chesapeake Bay Cruise

American Independence
American Cruise Lines
Starts: Baltimore, Maryland
Ends: Baltimore, Maryland
Ports of Call:
Baltimore, Yorktown, Williamsburg, Yorktown, Chesapeake Bay, Cambridge, St Michaels...

7 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

Jun 13, 2026

(Saturday)

7 Night Potomac River and Chesapeake Bay Cruise

American Independence
American Cruise Lines
Starts: Baltimore, Maryland
Ends: Washington DC, District of Columbia
Ports of Call:
Baltimore, Annapolis Maryland, St Michaels, Cambridge, Chesapeake Bay, Yorktown, Mount Vernon...

7 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More

Jun 20, 2026

(Saturday)

7 Night Potomac River and Chesapeake Bay Cruise

American Independence
American Cruise Lines
Starts: Washington DC, District of Columbia
Ends: Baltimore, Maryland
Ports of Call:
Washington DC, Yorktown, Chesapeake Bay, Cambridge, St Michaels, Annapolis Maryland, Baltimore

7 Nights


Add to Favorites
Compare Favorites
from

$4,610

per person
(double occupancy)
Includes taxes & fees
Learn More



Overlay Title