Get FREE Price Alerts

Subscribe to our weekly cruise deals email and enjoy FREE price change alerts and updates for this cruise and others like it.

We promise to protect your privacy and personal data. You can review our privacy policy here.

Modify Your Choices
Vacation Type


Filters
Destination
- Any Destination
Travel Dates
Narrow Date Range
Departure Port
- San Diego, CA
Cruise Length
- All Durations
Cruise Line
- Royal Caribbean Cruises
Cruise Ships
- All Cruise Ships

Cruises from San Diego


Sailings per page
2 Matched Sailings
Departing
Itinerary and Ship
Length
Save to
Favorites
Priced from

Oct 04, 2025

(Saturday)

16 Night Panama Canal Cruise

Radiance of the Seas
Royal Caribbean Cruises
4.1 based on 358 ratings
Starts: San Diego, California
Ends: Fort Lauderdale, Florida
Ports of Call:
San Diego, Cabo San Lucas, Mazatlan, Puerto Quetzal, Puntarenas, Cruising the Panama Canal, Colon...

16 Nights


Add to Favorites
Compare Favorites
Retail Price $2,721
Save $1,453
from

$1,268

per person
(double occupancy)
Includes taxes & fees
Learn More

Sep 19, 2025

(Friday)

13 Night Panama Canal Eastward Cruise

Serenade of the Seas
Royal Caribbean Cruises
3.9 based on 354 ratings
Starts: San Diego, California
Ends: Miami, Florida
Ports of Call:
San Diego, Puerto Vallarta, Huatulco, Puntarenas, Cruising the Panama Canal, Cartagena, Miami

13 Nights


Add to Favorites
Compare Favorites
Retail Price $1,818
Save $246
from

$1,572

per person
(double occupancy)
Includes taxes & fees
Learn More



Overlay Title